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MSC-Secretome Therapies
Bone marrow– and fat-derived cells and the signaling factors they release.
Autologous orthobiologics in Boulder, Colorado
Research-backed therapies that support your body's own repair.
We specialize in Autologous Therapies, your own cells, supporting your own body's repair; Bone marrow aspirate concentrate (BMAC), platelet-rich plasma (PRP), prolotherapy, and EPAT for orthopedic injuries, longevity, and complex medical conditions.
FDA-guidance aligned
Autologous, patient-derived
On-site biologics lab
Sterile, traceable processing
Affiliated research center
Non-profit · IRB trials
Honest, caring, effective.
★ ★ ★ ★ ★
“After struggling to find success with post-surgical stiffness and pain in my ankle, their treatments worked wonders. I now don't think about my ankle at all while I run, ski, hike, play basketball, and play tennis.”
Henry Locke
Google
★ ★ ★ ★ ★
“The team is so knowledgeable, caring, and thorough with all aspects of your visit. They are completely honest, instead of giving you false expectations. The client education is top notch!”
Lilli B
Google
★ ★ ★ ★ ★
“They look at you as a whole to get to the root of the problem instead of just pinpoint treating where you think hurts… I felt heard, seen, and valued as a person.”
Mandy Fiedler
Google
Our services
One Principle: Autologous
Our therapies are primarily autologous: your own cells supporting your own body's repair. Our orthopedic menu spans cellular, PRP, and adjunctive treatments. We also offer dedicated longevity medicine and biologic care for complex systemic conditions.
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PRP Treatments
Platelet-rich plasma, prepared and tuned to the target tissue.
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Additional Treatments
Non-cellular and energy-based options, often combined with biologics.
Meet your team
Expert care from people who'll know you by name.
Dr. Glowney is a board-certified physician who personally evaluates every patient. Ongoing care is delivered alongside Ryan Shiling, RN, co-founder and clinical staff, completing his Nurse Practitioner training in 2026.
Founder · Board-Certified Physician
Jason Glowney, MD, MSc, CAQSM
Internal Medicine
Sports Medicine
Research PI
Dr. Glowney moved to Colorado in 2009 for a Sports Medicine fellowship at the University of Colorado and has practiced biologic orthopedics in Boulder ever since. He is uniquely qualified in the field of orthobiologics, with extensive training in Internal Medicine (hematology and rheumatology), Emergency Medicine (orthopedic trauma), interventional orthopedics, and over ten years of post-fellowship experience.
Alongside medicine, he founded the Apeiron / Boulder Biologics Research Center, the clinic's affiliated non-profit running clinical-trials research on cellular therapy.
RoleFounder · PhysicianLeads every clinical decision
EducationMD · MSc, Applied MathematicsMaster's, University of Washington
CertificationsInternal Medicine · Sports Med (CAQSM)American Board of Internal Medicine
Clinical focusInterventional orthobiologicsImage-guided, patient-derived
FellowshipSports MedicineUniversity of Colorado · 2009
Research & writingPI, IRB cellular-therapy trialsAuthor, Mathematical Foundations and the Singularity (2024)
Co-Founder · Clinical Staff
Ryan Shiling, RN
RN
NP (Exp. 2026)
Orthopedic care
Ryan's clinical path runs the full length of acute and primary care, from EMT, to Medical Assistant, to Registered Nurse, and now completing Nurse Practitioner training (expected 2026). He co-founded Boulder Biologics with Dr. Glowney in 2018 and works across patient evaluations, pre-procedure consultations, and follow-up care.
An avid cyclist himself, Ryan understands athletes, how injuries actually disrupt training, what realistic return-to-sport looks like, and where biologic therapies fit in a competitive timeline.
RoleCo-Founder · Clinical StaffEvaluations, consults & follow-up
EducationBS, Health ScienceFlorida International UniversityBSNDenver College of NursingMSNUniversity of Cincinnati
CertificationsRegistered Nurse (RN)American Nurses AssociationNurse Practitioner (NP) Exp. 2026In training
Clinical focusOrthopedic regenerative medicineReturn-to-sport for athletes
What brings you in?
Find care for your condition.
Most patients arrive with a specific issue. Pick the closest match: we'll show you the therapies most relevant to your situation.
Orthopedic
Knee pain & arthritis
Osteoarthritis, meniscus injury, cartilage damage, post-surgical stiffness.
Bone marrow therapy · PRP · Hyaluronic acid →
Hip, back & SI joint pain
Hip osteoarthritis, sacroiliac dysfunction, lumbar facet pain, chronic low back.
PRP · Prolotherapy · Hydrodissection →
Shoulder & rotator cuff
Rotator cuff tears, labral injuries, frozen shoulder, shoulder arthritis.
Bone marrow therapy · PRP · EPAT →
Tendon & ligament injuries
Tennis & golfer's elbow, Achilles tendinopathy, plantar fasciitis, hamstring strain.
PRP · EPAT · Prolotherapy →
Systemic & medical
Concussion, TBI & CTE
Post-concussion syndrome, repetitive head trauma, cognitive recovery.
Cellular therapy · Medical applications →
Long COVID & post-viral
Persistent fatigue, brain fog, and inflammatory sequelae following infection.
Cellular therapy →
Eye & ocular surface
Moderate-to-severe dry eye, corneal epithelial defects, recurrent erosion, Sjögren's.
PRP eyedrops · Plasma eye drops →
Other systemic conditions
Autoimmune, inflammatory, and post-viral conditions we evaluate case by case.
Cellular therapy · Medical applications →
The Apeiron / Boulder Biologics Research Center · 501(c)(3) non-profit
1745 38th St., Boulder, Colorado
We don't just deliver biologic therapies, We also research them.
Dr. Glowney founded the Apeiron / Boulder Biologics Research Center, a non-profit running IRB-approved clinical trials in cellular therapy. Findings flow directly into the protocols you receive at the clinic.
Independent non-profit
The Research Center is a separate 501(c)(3) entity located in it's own facility and dedicated to advancing the science of autologous cellular therapy, no commercial conflicts.
IRB-approved trials
Investigator-led, protocol-driven studies on bone marrow–derived cellular therapy and adjacent biologics, with formal ethics review and outcome tracking.
Evidence into practice
Trial findings translate directly into clinical protocols at the practice, patients here benefit from a continuous research-to-care feedback loop.
Featured therapy
Bone Marrow Aspirate Concentrate, explained.
A small volume of your own bone marrow is aspirated from the hip under local anesthesia and image guidance. The aspirate is concentrated in our on-site lab, isolating the mesenchymal stromal cell–containing fraction (MSCs), platelets, and growth factors, then delivered with ultrasound or fluoroscopic guidance to the target tissue.
- In-clinic · single visit · local anesthesia
- On-site lab · sample never leaves the building
- Image-guided delivery to the target tissue
- Functional follow-up at 6 and 12 weeks
Also featured
Platelet-Rich Plasma, explained.
A small volume of your own blood is centrifuged to isolate a concentration of platelets and growth factors. The platelet-dense fraction is delivered with ultrasound guidance to support repair of cartilage, tendon, or ligament tissue.
- In-clinic · single visit · local anesthesia
- First-line autologous biologic for mild-to-moderate conditions
- Often used in combination with hyaluronic acid for knee OA
- Functional follow-up at 6 and 12 weeks
Orthobiologics at work
Cartilage signal recovery, bone-marrow edema improvement.
Imaging from one of our patients before and after a course of PRP therapy at our Boulder clinic.
This is an example of a patient's results from PRP therapy at Boulder Biologics. We caution that these results are the exception and would not be expected in more advanced or diffuse arthritis. Outcomes depend on patient selection, joint stage, and biological response.
Wondering if you're a candidate?
A 15-minute phone screen with our team, no charge, no obligation. We'll tell you honestly whether biologics fit your case or whether another path makes more sense.
Longevity medicine
Root-cause care for healthy aging.
A measurement-first approach to how you age, assessing the biomarkers that matter, then using autologous and lifestyle strategies to act on what we find. Care is led by Dr. Glowney and tailored to your goals.
Aging & epigenetics
How biological age and gene expression shift over time, and what we can measure.
Cardiometabolic biomarkers
Bloodwork that tracks heart, metabolic, and inflammatory health.
Hormone replacement
Assessment and management of age-related hormone changes.
Mitochondrial function
Supporting the cellular energy systems that decline with age.
Diet, sleep & exercise
The daily inputs that move your biomarkers the most.
Explore longevity care
A root-cause assessment and a plan built around your biology and goals.
Start with the overview →Frequently asked
Questions patients ask us most.
Cost, candidacy, recovery, and other common questions. If yours isn't here, ask us at consultation.
How much does it cost? Is it covered? +
Most insurance plans don't currently cover autologous biologic therapies: this is a patient-pay practice. We provide transparent pricing during your consultation, supply documentation for HSA / FSA reimbursement where applicable, and never bill you for anything that wasn't discussed up front.
What is BMAC, and how does it differ from PRP? +
PRP uses concentrated platelets and growth factors from your blood. BMAC uses MSC-containing material from your bone marrow. PRP is the first-line tool for many tendon and mild-to-moderate joint conditions; BMAC is typically considered when disease is more advanced or when subchondral bone is involved.
Is the procedure painful? +
Procedures are performed in-clinic under local anesthesia and ultrasound guidance. Most patients report mild post-procedural soreness for 24 to 72 hours. Light sedation is available for bone marrow aspiration if you prefer it.
Am I a candidate? +
Candidacy depends on your imaging, condition stage, prior treatments, and overall health. Every patient is evaluated by Dr. Glowney before any procedure is offered. We'll tell you honestly whether biologics fit your case or whether another path makes more sense.
How long does it take to see results? +
Biological response varies. Functional follow-up is typically scheduled at 6 and 12 weeks; many patients note progressive improvement over a 4–12 week window. Outcomes depend on patient selection, joint stage, and biological response.
Are you doing research too? +
Yes, Dr. Glowney also founded the Apeiron / Boulder Biologics Research Center, our affiliated non-profit running clinical-trials research on cellular therapy. The clinic and the research center are separate entities; trial participation, when available, follows IRB protocols.
Schedule a consultation
Talk through whether biologics might help.
Tell us briefly what's going on. A member of our team follows up within one business day to confirm an appointment with Dr. Glowney.
Visit
BCH Foothills Campus
4745 Arapahoe Ave, Suite 300
Boulder, CO 80303
Hours
Mon, Tue, Thu, Fri
8:00am – 5:00pm
Closed Wednesday