Jason Glowney, MD, MSc, CAQSM

Dr. Glowney moved to Colorado in 2009 for a Sports Medicine fellowship at the University of Colorado and has practiced biologic orthopedics in Boulder ever since. His training is unusually broad for the field: extensive clinical work in Internal Medicine (with focused exposure to hematology and rheumatology), Emergency Medicine (orthopedic trauma), and interventional orthopedics.

He co-founded Boulder Biologics in 2018 with Ryan Shiling, NP, building the clinic around a single principle: same-day, minimally manipulated, patient-derived biologic procedures, performed personally by the provider you see, with on-site lab processing. The practice does not use donor-derived cellular products, does not perform culture expansion, and does not make claims the evidence does not support.

Alongside the clinical practice, Dr. Glowney founded the Apeiron Research Center: a 501(c)(3) non-profit running IRB-approved clinical trials in cellular therapy. The Research Center is structurally independent of the clinic, with findings flowing back into clinical protocols through formal channels rather than commercial ones.

An unusual second discipline drives his passion: a graduate background in applied mathematics, with research interests in machine learning and AI methodology as applied to regenerative orthobiologics. His 2024 book, Mathematical Foundations and the Singularity details how mathematics ought to be the universal center of our understanding of existence.

• The whole person, and what you're working toward. His Internal Medicine training (hematology and rheumatology) brings your overall health into the plan, not only the injury. A competitive cyclist himself, he plans treatment around what you're getting back to, from a race season to a weekend on the trail.
• Evidence, stated plainly. A graduate background in applied mathematics shapes how he reads the research. When a question is open in the literature, he says so, and when an indication is investigational, he frames it that way.
• Performed by your provider. The provider you see prepares and performs your procedure, with biologics processed in our on-site lab. Dr. Glowney performs every bone marrow aspiration and his own patients' PRP, with image-guided delivery.
• Research-informed protocols. The clinic's protocols draw on the current published research in orthobiologics and cellular therapy, alongside findings from the Apeiron Research Center's own IRB-approved trials, and are updated as the evidence develops.

Dr. Glowney's research interests sit at three intersections:

• Autologous cellular therapy outcomes. IRB-approved, investigator-led trials of bone marrow– and adipose-derived biologic therapies for orthopedic and selected systemic indications. The Research Center's protocols emphasize careful patient selection, longitudinal outcome tracking, and conservative interpretation, outcomes flow into clinical practice through formal protocol updates, not anecdote.
• Machine learning & AI methodology in orthobiologics. Application of computational methods to the analysis of complex biological response data, patient phenotyping, outcome prediction, and the quantitative methodology of small-sample translational research.
• The science behind the clinical practice. Dr. Glowney authored the practice's deep clinical explainer on mesenchymal stromal cells, covering ISCT criteria, the first-pass effect, allogeneic immunogenicity, extracellular vesicles, senescence, and the blood–brain barrier, and the patient-facing articles in our Learn section.

Dr. Glowney has lived in Boulder for over 15 years with his wife and their two boys. He is a Masters national champion cyclist, racing primarily on the road and the track.