Founder · Board-Certified Physician
Jason Glowney, MD, MSc, CAQSM
Dr. Glowney is the founder of Boulder Biologics, a board-certified physician in Internal Medicine and Sports Medicine, and the principal investigator of the Apeiron / Boulder Biologics Research Center, an affiliated non-profit running clinical-trials research on cellular therapy.
3:2 landscape
01 · About
A career built across the line between research and clinical practice.
Dr. Glowney moved to Colorado in 2009 for a Sports Medicine fellowship at the University of Colorado and has practiced biologic orthopedics in Boulder ever since. His training is unusually broad for the field: extensive clinical work in Internal Medicine (with focused exposure to hematology and rheumatology), Emergency Medicine (orthopedic trauma), and interventional orthopedics: alongside more than a decade of post-fellowship experience in autologous biologic therapy.
He co-founded Boulder Biologics in 2018 with Ryan Shiling, RN, building the clinic around a single principle: same-day, minimally manipulated, patient-derived biologic procedures, performed by the physician personally, with on-site lab processing and image-guided delivery. The practice does not use donor-derived cellular products, does not perform culture expansion, and does not make claims the evidence does not support.
Alongside the clinical practice, Dr. Glowney founded the Apeiron / Boulder Biologics Research Center: a 501(c)(3) non-profit running IRB-approved clinical trials in cellular therapy. The Research Center is structurally independent of the clinic, with findings flowing back into clinical protocols through formal channels rather than commercial ones.
An unusual second discipline drives his passion: a graduate background in applied mathematics, with research interests in machine learning and AI methodology as applied to regenerative orthobiologics. His 2024 book, Mathematical Foundations and the Singularity details how mathematics ought to be the universal center of our understanding of existence.
02 · Training & credentials
Formal training.
- Boulder Center for Sports MedicineSports & orthopedic medicine
- CU Sports MedicineUniversity of Colorado
03 · Research focus
Where the clinical work meets the research.
Dr. Glowney's research interests sit at three intersections:
- Autologous cellular therapy outcomes. IRB-approved, investigator-led trials of bone marrow– and adipose-derived biologic therapies for orthopedic and selected systemic indications. The Research Center's protocols emphasize careful patient selection, longitudinal outcome tracking, and conservative interpretation, outcomes flow into clinical practice through formal protocol updates, not anecdote.
- Machine learning & AI methodology in orthobiologics. Application of computational methods to the analysis of complex biological response data, patient phenotyping, outcome prediction, and the quantitative methodology of small-sample translational research.
- The science behind the clinical practice. Dr. Glowney authored the practice's deep clinical explainer on mesenchymal stromal cells, covering ISCT criteria, the first-pass effect, allogeneic immunogenicity, extracellular vesicles, senescence, and the blood–brain barrier, and the patient-facing articles in our Learn section.
04 · Clinical philosophy
How he approaches a case.
Three principles run through every Boulder Biologics consultation:
- Conservative interpretation of the evidence. When a question is open in the literature, we say so. When an indication is investigational, we frame it that way. When the data don't support a claim, we don't make it, even when patients have heard the claim made elsewhere.
- Procedures performed by the physician. Dr. Glowney personally performs every bone marrow aspiration, every PRP preparation, every image-guided injection. The procedure is not delegated to a midlevel provider. This is unusual in the regenerative-medicine market and is a deliberate clinical-quality choice.
- The right answer is sometimes "not yet", or "not us." A meaningful number of consultations end with a recommendation other than biologic therapy: physical therapy, surgical consultation, a different clinic, or a clinical-trial referral. The job is to find the right next step, not to fill the schedule.
Same-day, minimally manipulated, autologous biologic therapy operates as a clinical procedure, not a manufactured drug. We work squarely within that framework, with full disclosure of regulatory status, and we don't make claims the evidence doesn't support.
05 · Selected writing
Patient-facing and clinical explainers.
Dr. Glowney writes the patient explainers and the clinical-science deep dive that anchor the Boulder Biologics Learn section. Each piece is written in the same language used in clinical letters and at consultation.
Mesenchymal Stromal Cells (MSCs), The Science
ISCT criteria, the first-pass effect, allogeneic immunogenicity, extracellular vesicles, senescence, and the blood–brain barrier. Clinician-leaning deep dive.
Is stem cell therapy FDA-approved?
A direct answer to the most-asked patient question, what the FDA has approved, what it hasn't, and what that means for regenerative-medicine clinics.
Autologous vs. donor-derived stem cells
The regulatory and clinical line between your own cells and donor cells, and why it determines where the FDA draws the line.
"Stromal" vs. "stem" cells
Why most peer-reviewed work has moved from "stem" to "stromal", and why the terminology shift matters for patients evaluating a clinic.
06 · Publications & talks
Selected work.
Book. Glowney J. Mathematical Foundations and the Singularity. Published 2024.
Clinical trials. Principal investigator on multiple IRB-approved studies of autologous bone marrow–derived cellular therapy through the Apeiron / Boulder Biologics Research Center. Active trial details available on request and registered with ClinicalTrials.gov where applicable.
Schedule a consultation.
Dr. Glowney reviews every case personally. A 45–60 minute consultation covers history, imaging, prior care, and an honest assessment of whether biologic therapy fits your situation.