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Condition overview · Orthopedics

Knee pain & arthritis

A short, plain-language brief on what we treat in the knee, the autologous biologic therapies that apply, and when one is, and isn't, the right path. For the full clinical depth on any therapy below, follow the link on its card.

Knee osteoarthritisMeniscus injuryCartilage damagePatellar tendinopathyPost-surgical stiffness

Therapies for this condition

Four autologous options for the knee.

Each one uses your own biologic material. The right choice depends on your imaging, stage of disease, prior treatments, and goals, Dr. Glowney walks through this with you in consultation.

01 · Cellular therapy

Bone marrow aspirate concentrate (BMAC)

MSC-containing · same-day · image-guided

A small volume of marrow is drawn from your iliac crest under local anesthesia, concentrated in our on-site lab, then delivered with ultrasound or fluoroscopic guidance to the target tissue.

  • Best fit when
  • Moderate knee OA with cartilage involvement
  • Failed PRP or wanting the most concentrated biologic
  • Subchondral bone marrow lesions on MRI
Read the full Bone marrow aspirate concentrate page →

02 · Platelet-rich plasma

Platelet-rich plasma (PRP)

Blood-derived · in-office · 60–90 min

Concentrated platelets and growth factors from your own blood, prepared in our lab and delivered into the target tissue under ultrasound guidance. The most-studied autologous biologic across orthopedic indications.

  • Best fit when
  • Early-to-moderate knee OA (Kellgren-Lawrence 2–3)
  • Patellar / quadriceps tendinopathy
  • Looking for the lowest-friction first biologic step
Read the full Platelet-rich plasma page →

03 · Combination · knee-specific

PRP + Hyaluronic acid

Single injection · biologic + viscosupplement

PRP combined with hyaluronic acid in a single intra-articular injection, pairing the signaling effect of platelets with the lubrication and load-distribution properties of HA. Purpose-built for the osteoarthritic knee.

  • Best fit when
  • Moderate knee OA with mechanical symptoms
  • Wanting symptom relief alongside biologic signaling
  • Have responded to either PRP or HA alone in the past
Read the full PRP + Hyaluronic acid page →

04 · Cellular therapy · adipose

Microfragmented adipose (mFAT)

Adipose-derived · same-day · image-guided

Your own fat, harvested by a brief mini-liposuction and microfragmented in our on-site lab the same day, then delivered into the joint under ultrasound guidance. A dense source of signaling cells that also adds a cushioning scaffold.

  • Best fit when
  • Diffuse or multi-compartment knee OA
  • Wanting an autologous cell source beyond marrow
  • When bone marrow harvest is less ideal that day
Read the full Microfragmented adipose page →

Is this you?

Find out if biologic therapy is the right next step for you.

A clear, condition-specific candidacy brief, so you can come to consultation already knowing where you stand and what to ask. If another path will serve you better, we'll point you to it.

Likely a good fit

  • Mild-to-moderate knee OA on imaging (KL grade 2–3)
  • Symptoms have outlasted physical therapy and activity modification
  • You want to delay or avoid a knee replacement, if reasonable
  • You're generally healthy, mobile, and willing to follow a 12-week protocol