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Condition overview · Orthopedics

Shoulder & rotator cuff

Shoulder pain can come from rotator cuff tendon problems (tendinopathy) and partial tears, labral injuries, frozen shoulder, or arthritis in the main shoulder joint (glenohumeral arthritis). Which biologic we recommend depends on the tissue involved and how long the problem has lasted.

Rotator cuff tendinopathyPartial-thickness cuff tearsLabral injuriesFrozen shoulder (adhesive capsulitis)Glenohumeral arthritis

Therapies for this condition

Three options for the shoulder.

We choose between bone marrow cellular therapy (BMAC) and PRP based on what is injured. A partial cuff tear, an arthritic joint, and a long-standing tendon problem each call for a different approach.

01 · Cellular therapy

Bone marrow aspirate concentrate (BMAC)

Contains stem cells (MSCs) · same-day · image-guided

We draw a small amount of bone marrow from the back of your hip bone (iliac crest) under local anesthetic, concentrate it in our on-site lab, and inject it into the target tissue using ultrasound or live X-ray (fluoroscopy) guidance.

  • Best fit when
  • Partial-thickness rotator cuff tears
  • Glenohumeral arthritis with cuff involvement
  • Failed prior PRP for cuff or joint
Read the full Bone marrow aspirate concentrate page →

02 · Platelet-rich plasma

Platelet-rich plasma (PRP)

Blood-derived · in-office · 60–90 min

Concentrated platelets and growth factors from your own blood, prepared in our lab and delivered into the target tissue under ultrasound guidance. There is more published research on PRP for joints and tendons than on any other autologous biologic.

  • Best fit when
  • Rotator cuff tendinopathy (no full-thickness tear)
  • Mild-to-moderate glenohumeral arthritis
  • First-line biologic step before considering BMAC
Read the full Platelet-rich plasma page →

03 · Autologous tissue · adipose

Microfragmented adipose (mFAT)

Adipose-derived · same-day · image-guided

Your own fat, microfragmented and rinsed in the same procedure and placed into the shoulder joint under ultrasound guidance as cushioning and structural support.

  • Best fit when
  • Wear in the main shoulder joint (the glenohumeral joint)
  • Wanting an option that adds cushioning to the joint
Read the full Microfragmented adipose page →

Talking it through

Find out if biologic therapy is the right next step for you.

These are the situations where biologic therapy most often comes up for this condition. Whether it fits you is something we work out together at your consultation. If another option makes more sense, we'll tell you.

What we look at together

  • Cuff pain or partial tear that has outlasted PT
  • Glenohumeral arthritis that hasn't yet reached replacement criteria
  • You're willing to follow a structured rehab plan for 12 weeks
  • Imaging shows tendon irritation or a partial tear. A full tear that has pulled back usually needs a surgeon's opinion first, and we'll help you get one.